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Using Regression Discontinuity in Time to Strengthen Real-World Evidence: A Case Study in Lung Cancer

Medical Decision Making

Published online on

Abstract

Medical Decision Making, Volume 46, Issue 5, Page 601-623, July 2026.
ObjectiveReal-world evidence is increasingly leveraged to assess treatment effectiveness outside of clinical trials, yet unmeasured confounders and missing data pose challenges to causal inference, which is particularly problematic when incorporating ...