Association between interstitial fibrosis/tubular atrophy (IFTA) on kidney biopsies and anti Ro60 antibody positivity in patients with lupus nephritis (LN)

Homa Timlin, Abbal Koiral, Avi Rosenber, Oluwadamilola Adisa, Mohamed G Atta, Ihab Kamel, Matthew Gross, Alana Dasgupta, Duvuru Geetha, Department of Rheumatology, Johns Hopkins University School of Medicine, Department of Nephrology, Johns Hopkins University School of Medicine, Department of Histopathology, Johns Hopkins University School of Medicine, Department of Radiology, Johns Hopkins University School of Medicine, Department of Histopathology, Ohio State University College of Medicine

Lupus: An International Journal

Published online on April 16, 2026

Abstract

Lupus, Ahead of Print.
BackgroundInterstitial fibrosis and tubular atrophy (IFTA) are key predictors of renal outcomes in lupus nephritis (LN), but serologic markers that identify patients at higher risk for tubulointerstitial damage are poorly defined. Anti-Ro60 antibodies are ...