Population-genomic stability of a closed-herd GGTA1-knock-out miniature pig line for xenotransplantation
Laboratory Animals: The international journal of laboratory animal science and welfare
Published online on April 08, 2026
Abstract
Laboratory Animals, Ahead of Print.
Genetically engineered pigs are essential donors for xenotransplantation, requiring phenotypic stability and genetic definition. We evaluated the newly establishedGGTA1-knock-out “XENO” line, maintained as a closed herd for >10 generations, against ...
Genetically engineered pigs are essential donors for xenotransplantation, requiring phenotypic stability and genetic definition. We evaluated the newly establishedGGTA1-knock-out “XENO” line, maintained as a closed herd for >10 generations, against ...