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Population-genomic stability of a closed-herd GGTA1-knock-out miniature pig line for xenotransplantation

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Laboratory Animals: The international journal of laboratory animal science and welfare

Published online on

Abstract

Laboratory Animals, Volume 60, Issue 3, Page 270-279, June 2026.
Genetically engineered pigs are essential donors for xenotransplantation, requiring phenotypic stability and genetic definition. We evaluated the newly establishedGGTA1-knock-out “XENO” line, maintained as a closed herd for >10 generations, against ...