Association Between Waist Circumference to Body Mass Index Ratio and Elevated Serum Transaminases Among Patients on Dolutegravir-based Antiretroviral Therapy in South Western Uganda

Charles Nkubi Bagenda, Pamella Kisakye, Hope Mudondo, Carol Nantongo, Milly Ketty Malinga, Charles Kigenyi, Isaac Nanyijuka, Ainea Ainebyona, Jazira Tumusiime, Michael Junior Mugisa, Elastus Ssemwanga, Lucas Ampaire, Vicent Mwesigye, Deusdedit Tusubira, Simon Peter Rugera

Journal of the International Association of Providers of AIDS Care (JIAPAC)

Published online on March 13, 2026

Abstract

Journal of the International Association of Providers of AIDS Care (JIAPAC), Volume 25, January-December 2026.
BackgroundDolutegravir (DTG)-based antiretroviral therapy (ART) has been associated with weight gain and obesity which are also linked to hepatocellular dysfunction. Despite these associations, the link between obesity indices and hepatocellular damage ...