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(-)-OSU6162 reduces freezing elicited by context-conditioned fear in rats

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Journal of Psychopharmacology

Published online on

Abstract

Journal of Psychopharmacology, Volume 39, Issue 12, Page 1491-1497, December 2025.
Objective:(-)-OSU6162 is an antagonist at dopaminergic D2receptors which – like other D2antagonists – dampens spontaneous activity in animals exploring a novel environment. However, unlike other D2antagonists, (-)-OSU6162 has unexpectedly been found to ...