Trace amine-associated receptor 1 (TAAR1) activation reduced mania-relevant hyperexploration and risky decision-making in dopamine transporter knockdown mice
Published online on August 26, 2025
Abstract
Journal of Psychopharmacology, Volume 39, Issue 12, Page 1449-1461, December 2025.
Background:Risky decision-making is a cardinal feature of bipolar disorder (BD), yet no targeted pharmacotherapies exist for this behavioral deficit. Dopamine transporter knockdown (DAT KD) mice reproduce the DAT hypoexpression profile of BD and ...
Background:Risky decision-making is a cardinal feature of bipolar disorder (BD), yet no targeted pharmacotherapies exist for this behavioral deficit. Dopamine transporter knockdown (DAT KD) mice reproduce the DAT hypoexpression profile of BD and ...