Intracerebroventricular knockdown of NPY1R disrupts NPY1R-GALR2/TrkB heteroreceptor complexes without affecting neuroplasticity or depressive-like behaviour
Published online on November 27, 2025
Abstract
Journal of Psychopharmacology, Volume 39, Issue 12, Page 1462-1475, December 2025.
Background:Neuropeptide Y1 receptor (NPY1R) heteroreceptor complexes with galanin receptor 2 (GALR2) and Tropomyosin receptor kinase B (TrkB) contribute to neuroplasticity and mood regulation.Aims:To determine whether transient intracerebroventricular (...
Background:Neuropeptide Y1 receptor (NPY1R) heteroreceptor complexes with galanin receptor 2 (GALR2) and Tropomyosin receptor kinase B (TrkB) contribute to neuroplasticity and mood regulation.Aims:To determine whether transient intracerebroventricular (...