Antidepressant initiation and the risk of treatment-emergent mania in children and adolescents with depression: A real-world cohort study
Published online on November 12, 2025
Abstract
Journal of Psychopharmacology, Volume 39, Issue 12, Page 1378-1386, December 2025.
Background:Whether starting antidepressants (ADs) precipitates treatment-emergent mania (TEM) in young people with major depressive disorder (MDD) is still debated. A recent nationwide cohort study found no short-term risk, but its transferability to more ...
Background:Whether starting antidepressants (ADs) precipitates treatment-emergent mania (TEM) in young people with major depressive disorder (MDD) is still debated. A recent nationwide cohort study found no short-term risk, but its transferability to more ...