Adjunctive Muscle Relaxants and Opioid Use Following Total Knee Arthroplasty

Carlina J. Grindeland, Colin P. Murphy, Jeremy W. Grindeland, Hallie Thompson, Devendranath Mannuru, Sanford Health, University of North Dakota School of Medicine and Health Sciences, Grand Forks

Journal of Pharmacy Practice

Published online on March 31, 2026

Abstract

Journal of Pharmacy Practice, Ahead of Print.
The opioid-abuse crisis in the United States is an area of concern within orthopedic practices. Postoperative pain following total knee arthroplasty (TKA) is one of the most common scenarios for opioid prescribing by orthopedic surgeons. Our study ...