Physician Perspectives on Real-World Evidence for Prescribing to Older Patients

Leah Z. Rand, Junyi Wang, Steven Woloshin, Shirley V. Wang, Jonathan J. Darrow, Aaron S. Kesselheim, Program on Regulation, Therapeutics and Law , Department of Medicine, Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women, s Hospital, Harvard Medical School, The Dartmouth Institute, Geisel School of Medicine, Department of Medicine, Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women, s Hospital

Journal of Pharmacy Practice

Published online on January 19, 2026

Abstract

Journal of Pharmacy Practice, Ahead of Print.
BackgroundAvailable evidence for many prescription drugs comes from clinical trials that often exclude older patients. Real-world evidence (RWE) generated post-approval can provide new evidence on effectiveness and safety for these populations. We sought ...