Hypersensitivity reactions to chemotherapy and biologics: Outcomes and safety of 927 desensitization in Mexico

Rosalaura Villarreal-González, Leslie Astrid De la Fuente, Diana Cadenas-García, Itzayana Ortega-Franco, Marianela Madrazo-Morales, Kathia Sáenz-Cantú, Meryl Cadena-Rosales, Rafael Piñeiro Retif, Oscar Vidal-Gutiérrez, Faculty of Medicine, Oncology Service, Hospital Universitario , Dr José Eleuterio González, Universidad Autónoma de Nuevo León, Nuevo León

Journal of Oncology Pharmacy Practice

Published online on July 28, 2025

Abstract

Journal of Oncology Pharmacy Practice, Ahead of Print.
IntroductionChemotherapy and monoclonal antibodies are increasingly associated with hypersensitivity reactions (HSRs), including anaphylaxis. Desensitization modulates allergic responses to drugs, facilitating temporary tolerance to full therapeutic ...