Impact of gastric acid suppressants on oral protein kinase inhibitor efficacy: A systematic review and meta-analysis of plasma concentrations and survival outcomes
Journal of Oncology Pharmacy Practice
Published online on February 02, 2026
Abstract
Journal of Oncology Pharmacy Practice, Ahead of Print.
IntroductionWhile the co-administration of oral protein kinase inhibitors (PKIs) and gastric acid suppressants (GASs) is widespread, the impact of GASs on the pharmacokinetics and survival outcomes of PKIs has remained systematically uninvestigated. The ...
IntroductionWhile the co-administration of oral protein kinase inhibitors (PKIs) and gastric acid suppressants (GASs) is widespread, the impact of GASs on the pharmacokinetics and survival outcomes of PKIs has remained systematically uninvestigated. The ...