Exploring the causal effect of genetically predicted blood and cerebrospinal fluid metabolites and metabolic pathways on intracranial aneurysm

Lu Ding, Wei Cao, Zhou Zhou, Zhaojun Mei, Bo Chen, Xinyu Lu, Wei Chen, Department of General Practices, the Affiliated People, s Hospital of Jiangsu University, Department of Neurology, the Affiliated People, s Hospital of Jiangsu University, Department of Neurosurgery, the Affiliated People, s Hospital of Jiangsu University

Journal of International Medical Research

Published online on April 29, 2026

Abstract

Journal of International Medical Research, Volume 54, Issue 4, April 2026.
ObjectivePrevious studies have identified significant alterations in metabolites in patients with intracranial aneurysm. This study aimed to evaluate the causal relationships of metabolites in both blood and cerebrospinal fluid with intracranial aneurysm ...