Adverse Childhood Experiences, Depression and Subjective Cognitive Decline by Gender: A Moderated Mediation Analysis

Monique J. Brown, Darlingtina K. Esiaka, Jaya Viswanathan, Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, South Carolina SmartState Center for Healthcare Quality, Arnold School of Public Health, University of South Carolina, Rural Health Research Center, Arnold School of Public Health, University of South Carolina, Office for the Study on Aging, Arnold School of Public Health, University of South Carolina, Centre for Health Systems Research , University of the Free State, South Africa, Center for Health Equity Transformation, University of Kentucky College of Medicine, Department of Behavioral Sciences, University of Kentucky College of Medicine, Independent Researcher

Journal of Applied Gerontology

Published online on October 06, 2025

Abstract

Journal of Applied Gerontology, Ahead of Print.
Studies assessing depression as a mediating factor between adverse childhood experiences (ACEs) and subjective cognitive decline (SCD) are lacking. Therefore, the aims of this study were to: (1) determine the mediating role of depression in the ...