The Moderating Effect of Physical Activity on the Association Between Cognition and Depression Among Middle-Aged and Older Adults: A Differential Analysis by European Regions

Marcelo de Maio Nascimento, Adilson Marques, Gerson Ferrari, Élvio Rúbio Gouveia, Andreas Ihle, Department of Physical Education, Federal University of Vale do São Francisco, Swiss Center of Expertise in Life Course Research LIVES, Faculdade de Motricidade Humana, Universidade de Lisboa, Núcleo de Investigación en Ciencias del Movimiento, Universidad Arturo Prat, Escuela de Ciencias de la Actividad Física, el Deporte y la Salud, Universidad de Santiago de Chile, Faculty of Health Sciences, Universidad Autónoma de Chile, Department of Physical Education and Sport, University of Madeira, Laboratory of Robotics and Engineering Systems , Interactive Technologies Institute, Department of Psychology, University of Geneva, Center for the Interdisciplinary Study of Gerontology and Vulnerability, University of Geneva

Journal of Applied Gerontology

Published online on August 12, 2025

Abstract

Journal of Applied Gerontology, Ahead of Print.
This study aimed to investigate the moderating effect of moderate-to-vigorous physical activity (MVPA) on the association between cognition and depression in individuals aged 50 years or older living in 27 European countries and to explore differences ...