Do Depression and Anxiety Mediate the Relationship between Multi-dimensional Chronic Pain and Subjective Cognitive Decline?

Jianli Wu, Staja Q. Booker, Michael Marsiske, Ellen L. Terry, Ann L. Horgas, College of Nursing, University of Florida, College of Public Health , Health Professions, University of Florida

Journal of Applied Gerontology

Published online on December 23, 2025

Abstract

Journal of Applied Gerontology, Ahead of Print.
BackgroundThe relationship between multidimensional chronic pain (frequency, intensity, and interference) and subjective cognitive decline remains unclear, and the roles of depression and anxiety in this relationship are still unknown.ObjectiveTo ...