The Effect of Preanalytical Processes on Nucleic Acid Quality in Biomarker Analysis With Next-Generation Sequencing
International Journal of Surgical Pathology
Published online on April 20, 2026
Abstract
International Journal of Surgical Pathology, Ahead of Print.
BackgroundPreanalytical processes—including sample collection, fixation, and handling—significantly influence the integrity of nucleic acids, which in turn impacts the accuracy of next-generation sequencing (NGS)-based biomarker analyses. Though commonly ...
BackgroundPreanalytical processes—including sample collection, fixation, and handling—significantly influence the integrity of nucleic acids, which in turn impacts the accuracy of next-generation sequencing (NGS)-based biomarker analyses. Though commonly ...