The Effect of Preanalytical Processes on Nucleic Acid Quality in Biomarker Analysis With Next-Generation Sequencing
International Journal of Surgical Pathology
Published online on April 20, 2026
Abstract
International Journal of Surgical Pathology, Volume 34, Issue 6, Page 1520-1528, September 2026.
BackgroundPreanalytical processes—including sample collection, fixation, and handling—significantly influence the integrity of nucleic acids, which in turn impacts the accuracy of next-generation sequencing (NGS)-based biomarker analyses. Though commonly ...
BackgroundPreanalytical processes—including sample collection, fixation, and handling—significantly influence the integrity of nucleic acids, which in turn impacts the accuracy of next-generation sequencing (NGS)-based biomarker analyses. Though commonly ...