FLCN-Mutated Tumors in Smith-Magenis Syndrome: A Case Report of FLCN-Associated Pathogenesis
International Journal of Surgical Pathology
Published online on March 13, 2026
Abstract
International Journal of Surgical Pathology, Volume 34, Issue 5, Page 1303-1309, August 2026.
Birt-Hogg-Dubé syndrome and Smith-Magenis syndrome both involve the 17p11.2 chromosomal region, withFLCNgermline pathogenic variants causing Birt-Hogg-Dubé syndrome andRAI1deletions causing Smith-Magenis syndrome. When Smith-Magenis syndrome deletions ...
Birt-Hogg-Dubé syndrome and Smith-Magenis syndrome both involve the 17p11.2 chromosomal region, withFLCNgermline pathogenic variants causing Birt-Hogg-Dubé syndrome andRAI1deletions causing Smith-Magenis syndrome. When Smith-Magenis syndrome deletions ...