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Digitally Assessed Nucleolar Size Compared to Traditional Pathologist WHO Grade Allocation in Clear Cell Renal Cell Carcinoma

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International Journal of Surgical Pathology

Published online on

Abstract

International Journal of Surgical Pathology, Volume 34, Issue 6, Page 1435-1439, September 2026.
Traditional WHO grading for renal cell carcinoma (RCC), largely based on nucleolar prominence, has well-known intraobserver and interobserver variability. In the era of digital pathology, quantitative guidelines may be more accurate and reproducible. ...