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Bayesian design and analysis of two-arm cluster randomised trials using assurance: Extension to binary outcomes and comparison of Markov chain Monte Carlo and Integrated Nested Laplace Approximations

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Clinical Trials: Journal of the Society for Clinical Trials

Published online on

Abstract

Clinical Trials, Ahead of Print.
Background/Aims:Bayesian designs for clinical trials using assurance to choose the sample size have been proposed in various trial contexts. Assurance allows for the incorporation of uncertainty on both the treatment effect and nuisance parameters into ...