Predictors of benefits and safety events from participation in a lifestyle therapy trial for adults with depression: A secondary analysis of the CALM randomised controlled trial

Lara K Radovic, Madeleine L Connolly, Lauren M Young, Marita Bryan, Wolfgang Marx, Megan Turner, Dean Saunders, Sophie Mahoney, Rachel Fiddes, Tayla John, Amelia McGuinness, Tetyana Rocks, Deborah N Ashtree, Adrienne O, Neilon behalf of the CALM Investigator team

Australian & New Zealand Journal of Psychiatry

Published online on April 15, 2026

Abstract

Australian & New Zealand Journal of Psychiatry, Ahead of Print.
Objective:Lifestyle-based interventions are increasingly popular for treating depression, yet a comprehensive evaluation of who benefits or may be harmed is limited. This study examined predictors of benefits and safety events, and the types of these ...