Are cognitive deficits more severe among people with treatment-resistant schizophrenia than treatment responders?

Ananthakrishnan KolothSir Charles Gairdner Hospital, North Metropolitan Health Service, Kim Yeak, Bentley Health Service, Somayyeh AzimiClinical Research Centre, North Metropolitan Health Service Mental Health, Radhakrishnan Koloth, Peel and Rockingham Kwinana Health Service, Aneeka AlexanderNorthern Beaches Hospital, Milan DragovicClinical Research Centre, North Metropolitan Health Service Mental Health, Alexander Panickacheril John, Bentley Health Service, and Medical School, The University of Western Australia

Australasian Psychiatry

Published online on October 30, 2025

Abstract

Australasian Psychiatry, Volume 34, Issue 2, Page 162-168, April 2026.
BackgroundGiven the robust association of cognitive deficits (CD) with community functioning in people with schizophrenia and the inconsistent findings from the limited research on CD among people with treatment-resistant schizophrenia (TRS), we evaluated ...