Physical Activity and Physical Fitness in Children and Adolescents Diagnosed With Sickle Cell Disease: A Scoping Review

Ariane Levesque, Deepika Pugalenthi Saravanan, Peri Newman, Lauryn E. Six, Yevgeniya Bamme, Smita Dandekar, Kate J. Krause, Maria Chang Swartz, Gayle M. Smink, Maxime Caru, Department of Pediatrics, Division of Hematology and Oncology, Penn State Health Children, s Hospital, Penn State College of Medicine, Penn State Cancer Institute, Division of Pediatric Hematology, The Herman and Walter Samuelson Children, s Hospital at Sinai, Research Medical Library, The University of Texas MD Anderson Cancer Center, Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Department of Public Health Sciences, Penn State University College of Medicine

American Journal of Lifestyle Medicine

Published online on August 28, 2025

Abstract

American Journal of Lifestyle Medicine, Volume 20, Issue 6, Page 843-868, August 2026.
Introduction:Research on the benefits of physical activity (PA) for children diagnosed with sickle cell disease (SCD) remains divided. This scoping review aimed to describe PA and physical fitness assessments, detail existing PA interventions, and ...