Optimizing Palliative Cancer Surgery Trial Completion: Lessons Learned From Qualitative Content Analysis of S1316 – Comparative Effectiveness Trial for Malignant Bowel Obstruction

Mohammad Saad Farooq, Neda Amini, Virginia Sun, Gary B. Deutsch, Jeremiah L. Deneve, Marcia Grant, Kathryn B. Arnold, Angeles Alvarez Secord, Garnet Anderson, Robert S. Krouse, Division of Endocrine and Oncologic Surgery, Hospital of the University of Pennsylvania, Department of Surgery, Geisinger Medical Center, Division of Nursing Research and Education, Department of Population Sciences, City of Hope Comprehensive Cancer Center, Division of Surgical Oncology, NYU Langone Hospital - Long Island, Division of Surgical Oncology, University of North Carolina, Chapel Hill, SWOG Statistics and Data Management Center, Fred Hutchinson Cancer Center, Division of Gynecologic Oncology, Duke Cancer Institute, Duke University Health System, Division of Public Health Science, Fred Hutchinson Cancer Center, Department of Surgery, University of Pennsylvania, Leonard Davis Institute of Health Policy, Michael J. Crescenz Veterans Affairs Medical Center

American Journal of Hospice and Palliative Medicine®

Published online on October 29, 2025

Abstract

American Journal of Hospice and Palliative Medicine®, Ahead of Print.
BackgroundMalignant bowel obstruction (MBO) is a complex clinical entity and there remains a relative lack of high-quality comparative trials on surgical management, in part due to a heterogeneous patient population and different treatment modalities ...