MetaTOC stay on top of your field, easily

American Journal of Physiology-Gastrointestinal and Liver Physiology, Ahead of Print.

American Journal of Physiology-Cell Physiology, Ahead of Print.

American Journal of Physiology-Cell Physiology, Ahead of Print.

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Volume 331, Issue 1, Page R86-R101, July 2026.

["The Journal of Physiology, EarlyView. ", "\nAbstract figure legend The ultrarapid delayed rectifier potassium current (IKur) has long been considered an atrial‐specific current with no functional role in the ventricles, despite evidence of its expression in ventricular myocytes. In the present study we challenged this prevailing concept and investigated the potential role of IKur in ventricular repolarization. Cellular electrophysiology and molecular cardiology experiments were performed on cardiac preparations obtained from dog and undiseased human hearts. We show clear evidences that IKur current is present in the ventricular myocardium at both molecular and functional levels. We confirm the presence of IKur current in atrial and ventricular tissue using immunochemistry, standard microelectrode and patch‐clamp techniques. We also confirm that IKur current plays a significant role in ventricular repolarization reserve, as under conditions where the repolarization reserve was pharmacologically attenuated (by inhibiting IKr current), additive inhibition of IKur induces early afterdepolarizations (EADs), indicating that its blockade might have a significant proarrhythmic side effect.\n\n\n\n\n\n\n\n\n\nAbstract\nThe ultrarapid delayed rectifier potassium current (IKur) has long been considered an atrial‐specific current with no functional role in the ventricles, despite evidence of its expression in ventricular myocytes. In the present study we challenged this prevailing concept and investigated the potential role of IKur in ventricular repolarization. Kv1.5 protein expression was determined by immunocytochemistry in canine and undiseased human cardiac tissue samples. Action potentials (APs) were recorded using conventional microelectrode techniques in canine and human cardiac preparations, and ion currents were measured using the whole‐cell patch‐clamp technique in isolated cardiomyocytes. In silico simulations were performed to investigate the role of the IKur current using a human ventricular model (T‐WorldIKur). Kv1.5 protein expression was detected in canine atrial, ventricular and Purkinje fibre cells, as well as in undiseased human left ventricular myocardium. In canine atrial preparations IKur inhibition shifted the plateau phase of the AP into the positive voltage direction and consequently shortened AP duration. Application of 100 µM 4‐aminopyridine (4‐AP) revealed ionic currents of similar magnitude in ventricular myocytes and Purkinje fibres, which were attributed to IKur. Inhibition of IKur caused prolongation of the APs recorded from endocardial and midmyocardial preparations, as well as from Purkinje fibres. Under conditions of attenuated repolarization reserve IKur inhibition induced augmented repolarization lengthening and frequent early afterdepolarizations (EADs). In silico modelling data regarding the IKur inhibition‐evoked EAD formations are in good agreement with the experimental findings. IKur is present and functionally active in ventricular myocardium and may represent a significant contributor to ventricular repolarization reserve.\n\n\n\n\n\n\n\n\n\nKey points\n\nThe ultrarapid delayed rectifier potassium current (IKur) has long been considered an atrial‐specific current with no functional role in the ventricles.\nIn the present study, we challenged this prevailing concept and investigated the potential role of IKur in ventricular repolarization. Cellular electrophysiology and molecular cardiological experiments were performed on cardiac preparations obtained from dog and undiseased human hearts.\nWe present clear evidence that IKur current is present in the ventricular myocardium at both molecular and functional levels. We also confirm that IKur current plays a significant role in ventricular repolarization reserve.\nWe concluded that IKur is present and functionally active in ventricular myocardium and may represent a significant contributor to ventricular repolarization reserve.\n\n\n"]

["The Journal of Physiology, EarlyView. ", "\nAbstract figure legend Healthy adults received combined anodal transcranial direct current stimulation (tDCS) over the left premotor cortex and peripheral nerve stimulation (PNS) of the right ulnar nerve during action observation, followed by two action execution blocks. The main experimental conditions included tDCS + PNS with action observation, sham tDCS + sham PNS with action observation, and tDCS + PNS with landscape observation; control experiments isolated the effects of tDCS or PNS alone during action observation. Corticospinal excitability, indexed by motor‐evoked potentials (MEPs), intracortical facilitation (ICF) and short‐interval intracortical inhibition (SICI) were assessed at baseline (T0), immediately after the intervention (T1) and after the first execution block (T2), and reaction time was measured during the two execution blocks (RT1, RT2). Combined tDCS + PNS during action observation enhanced observation–execution‐related cortical excitability and improved motor performance.\n\n\n\n\n\n\n\n\n\nAbstract\nAction observation and execution, transcranial direct current stimulation (tDCS) and peripheral nerve stimulation (PNS) enhance motor performance. This study aimed to investigate the effect of concurrent tDCS over the premotor cortex (PMC) and PNS during action observation on motor cortex excitability and motor performance, and its underlying mechanisms. One hundred and twenty‐eight healthy adults were randomly assigned to tDCS + PNS combined with presentation of a landscape picture (tDCS + PNSlandscape), and tDCS + PNS, tDCSsham+ PNSsham, tDCSsham + PNS and tDCS + PNSsham combined with action observation, all followed by two action execution blocks. Motor‐evoked potentials (MEPs), intracortical facilitation (ICF) and short‐interval intracortical inhibition (SICI) were assessed before interventions (T0), immediately after interventions (T1) and after the first action execution block (T2). Reaction times were recorded for both action execution blocks (RT1 and RT2). tDCS + PNS significantly increased MEP amplitudes at T1 and T2 compared to tDCSsham + PNSsham and tDCS + PNSlandscape. ICF increased at T1 in the tDCS + PNS group compared to tDCSsham + PNSsham and tDCS + PNSlandscape, as well as at T2 relative to tDCSsham + PNSsham. RT1 and RT2 of the action execution task in the tDCS + PNS group were significantly shorter compared to the tDCSsham + PNSsham group. A significant negative relationship between the change in RT and MEP amplitudes emerged at T2 in the tDCS + PNS group. Concurrent application of tDCS and PNS during action observation induced transient neuroplastic alterations in the primary motor cortex and improved motor performance.\n\n\n\n\n\n\n\n\n\nKey points\n\nThe integration of motor observation and action execution enhances motor performance, with similar brain networks playing key roles in this process. However, the effect of concurrent application of transcranial direct current stimulation (tDCS) over the premotor cortex and peripheral nerve stimulation (PNS) during action observation on observation–execution‐related motor cortex excitability and motor performance and the underlying mechanism is lacking in the literature.\nSimultaneous application of brain (anodal tDCS over the premotor cortex) and peripheral nerve (PNS over the ulnar nerve) stimulation during action observation induced transient neuroplastic alterations in the primary motor cortex and improved motor performance.\nSince this dual‐stimulation method strengthens brain pathways related to movement, it could be especially useful for people recovering from conditions like stroke, where active movement is limited.\n\n\n"]

["The Journal of Physiology, EarlyView. ", "\nAbstract figure legend Sounds of different frequencies elicit spatially distinct patterns of neural activity within the inferior colliculus aligned to the tonotopic organization of afferent projections. Sound‐evoked neural responses can be visualized in awake mice that express fluorescent Ca2+ sensors. We find that neural activity patterns produced in response to pure tones are not fixed but evolve during the stimulus, with discrete groups of neurons activated during onset (ON) and offset (tdOFF) periods. Sound‐evoked lateral inhibition appears to shape tdOFF responses, as tdOFF neurons were suppressed by sound and spatially clustered in sideband regions at sound offset. Loud noise‐induced hearing loss reshaped the spatiotemporal characteristics of sound processing, abolishing both sideband suppression and tdOFF responses, but preserving ON response patterns and amplitudes. This prioritization of ON responses helps preserve sound processing in hearing loss but may contribute to worsened acuity and related hearing disorders, such as hyperacusis and tinnitus.\n\n\n\n\nAbstract\nThe parsing of sensory information into discrete topographic domains is a fundamental principle of sensory processing. In the auditory cortex, these domains evolve during a stimulus, with the onset and offset of tones evoking distinct spatial patterns of neural activity. However, it is not known where in the auditory system this spatial segregation occurs or how these dynamics are affected by hearing loss. Using widefield single photon neuronal Ca2+ imaging in the inferior colliculus (IC) of awake mice, we found that pure tone stimuli elicited both spatially constrained neural activity within isofrequency bands and simultaneous sideband suppression. At cessation of the stimulus, offset responses emerged within the region of sideband suppression, demonstrating that simple stimuli elicit spatiotemporally distinct neural activity patterns to represent the presence of sound and sound termination. Because sound frequency is spatially encoded in the IC, this spatial shift creates a tonotopically distinct offset (tdOFF) response relative to sound onset. High‐resolution two‐photon Ca2+ imaging confirmed that tdOFF neuron activity in the sideband region was suppressed during sound and elevated above baseline after stimulus termination, raising the possibility that rebound excitation could contribute to this post‐stimulus activation. Loud noise exposure – a common model of hearing loss – abolished both sideband suppression and tdOFF responses. These results show that hearing loss profoundly reshapes the spatiotemporal pattern of sound processing by altering sideband activity. This preferential loss of sideband suppression and tdOFF activation after sound‐induced injury in the auditory midbrain may contribute to hyperacusis and tinnitus by promoting neuronal hyperactivity.\n\n\n\n\n\n\n\n\n\nKey points\n\nSensory systems encode different features of stimuli by activating distinct neural networks.\nSound onsets and offsets elicit distinct neural patterns in the auditory cortex, although it is unclear where this separation originates or how it may change with hearing loss.\nUsing in vivo widefield Ca2+ imaging in awake mice, we find that pure tone stimuli evoke spatiotemporally distinct on and off patterns of neural activity in the auditory midbrain.\nNeurons active during stimulus offset were suppressed by sound in sideband regions, raising the possibility that rebound excitation may contribute to this post‐stimulus activation.\nBoth sideband suppression and off responses were preferentially abolished following noise‐induced hearing loss, raising the possibility that these changes may contribute to hearing loss‐related syndromes such as tinnitus and hyperacusis.\n\n\n"]

American Journal of Physiology-Renal Physiology, Ahead of Print.

American Journal of Physiology-Lung Cellular and Molecular Physiology, Ahead of Print.

American Journal of Physiology-Endocrinology and Metabolism, Ahead of Print.

["Health Expectations, Volume 29, Issue 4, August 2026. ", "\nABSTRACT\n\nBackground\nTelehealth can mitigate healthcare access barriers that contribute to persistent rural health inequities. However, a limited understanding of telehealth barriers and preferences hinders the implementation of effective programs in rural communities. We conducted a formative evaluation to identify barriers and facilitators to telehealth adoption in an underserved rural setting.\n\n\nMethods\nWe used a mixed‐methods design including surveys and in‐depth semi‐structured interviews with rural community stakeholders. The survey assessed telehealth utilisation, perceptions, technology access and barriers using Likert‐type scales. Survey data were analysed descriptively, and interview data were examined thematically across the Unified Theory of Acceptance and Use of Technology (UTAUT) constructs.\n\n\nFindings\nSurvey respondents (n = 59) were primarily female (73.2%), and White (73.2%), with a mean age of 61 years. Over half (51.8%) reported annual incomes below $20,000, and 18.6% lacked home internet access. While 59.3% had heard of telehealth, only 42.4% had used it. Among users, 61.9% reported satisfaction, and 71.4% agreed or strongly agreed that communication with providers was adequate. Key barriers included limited internet connectivity (72.8%), technology challenges (66.6%) and lack of knowledge about accessing telehealth (62.5%). Interview participants (n = 8) emphasised that trust and comfort with providers were central to acceptance and highlighted telehealth's convenience in reducing transportation barriers.\n\n\nConclusion\nIn this study population, telehealth was generally acceptable, with trust and comfort with the provider driving acceptance. Barriers were primarily related to connectivity, infrastructure and digital literacy. Consistent with larger studies, these findings support investments in broadband access, digital literacy, technical support and building patient confidence in virtual care.\n\n\nPatient or Public Contribution\nMembers of the public were involved in the design, recruitment and dissemination phases of this study. We partnered with local community organisations serving rural populations to inform recruitment strategies and to distribute surveys to community members with lived experience of healthcare access barriers. Community stakeholders also participated directly in the research through survey completion and in‐depth interviews, providing critical insights into telehealth use, barriers and preferences. While the public was not involved in the initial study design or data analysis, their perspectives shaped the interpretation of findings, particularly regarding trust, technology use and access challenges. To support dissemination and ensure accessibility of results, we developed a one‐page summary of findings that was shared with participating community partner sites for distribution back to the communities involved.\n"]

["Health Expectations, Volume 29, Issue 4, August 2026. ", "\nABSTRACT\n\nBackground\nBuilding capacity through training and education is recommended to support meaningful engagement of patient partners in health research. The Patient and Community Engagement Research (PaCER) programme is a 12‐month initiative that enables patients and community members to co‐design and conduct qualitative health research projects. Learners are sponsored by clinician researchers, community organisations, and/or jurisdictional health organisations. This study aimed to assess the experiences and impact of the PaCER programme on: (1) past learners' personal development and engagement in health research; and (2) sponsors' research programmes.\n\n\nMethods\nWe conducted a qualitative impact evaluation involving past learners (alumni) and sponsors of the PaCER programme from 2019 to 2024. A purposive sampling strategy was used, whereby selected alumni and sponsors from the 2019–2024 cohorts were invited to participate in an online semi‐structured interview. Sponsors and alumni with diverse characteristics, including variation in age, ethnicity, educational attainment, and geographic location were invited. The interview guide included questions on the experiences in the PaCER programme, post‐programme research activities, and perceptions of the programme's impact. Data were analysed using a reflexive thematic analysis approach.\n\n\nResults\nEighteen participants (12 PaCER alumni and 6 sponsors) were interviewed, and four main themes were identified: (1) seeing the value of the training programme; (2) Diverse people and groups working together; (3) Learner readiness and capacity; (4) Academic opportunities for learners and career growth. Alumni described significant personal impact, empowerment, academic contributions, and increased access to meaningful patient partner opportunities. Alumni reported co‐authoring publications and presenting their work at academic conferences and to various stakeholders, including health system leadership. Many alumni had no prior experience with qualitative participatory research, and participation in the programme supported the development of these research skills. Sponsors also noted impacts on their research programmes, such as securing additional funding informed by PaCER project findings.\n\n\nConclusion\nThe findings demonstrate that structured, experiential training for patients and community members supports meaningful engagement in health research, contributes to sustained capacity development, and positively influences the patient‐oriented research landscape.\n\n\nPatient or Public Contribution\nPatient partners were involved in the design and conduct of the study (data collection), analysis and interpretation of the data, and in the preparation of this manuscript.\n"]

["Health Expectations, Volume 29, Issue 4, August 2026. ", "\nABSTRACT\n\nBackground\nCo‐design has become a prominent approach in mental health research, policy and service development, aiming to centre lived experience within decision‐making processes. Despite its promise, co‐design practices often fall short, with reports of tokenism, constrained participation and limited influence. These limitations reflect deeper epistemic and relational inequities within mental health systems.\n\n\nDiscussion\nThis commentary argues that the challenges of co‐design can be understood through the lens of epistemic injustice, where certain forms of knowledge, particularly lived experience, are systematically devalued. Drawing on restorative justice principles, the paper proposes a relational and ethical reframing of participation. Restorative approaches—centred on truth‐telling, acknowledgement and repair—offer a means to address the relational harms and power imbalances that undermine meaningful participation. Building on this, the Cycle of Equitable Codesign is introduced as a staged framework comprising: (1) acknowledgement and truth‐telling, (2) restoration and relational repair and (3) co‐design and collective future‐making. The model emphasises the importance of timing, power and relational conditions in shaping equitable participation.\n\n\nConclusion\nRepositioning co‐design within a restorative framework highlights the need to move beyond procedural inclusion towards ethically grounded and relationally just practice. Addressing epistemic injustice is essential for co‐design to achieve its transformative potential in mental health systems.\n\n\nPatient and Public Contribution\nThis commentary is informed by existing literature on co‐design and lived experience participation in mental health. It centres and reflects on the reported experiences of people with lived experience of mental health challenges. Although no direct formal patient or public involvement was undertaken in the development of this paper, it was informed following extensive informal communication with those who have a lived experience of mental health challenges and codesign participation over the prior 18 months.\n"]

["Journal of Community Psychology, Volume 54, Issue 5, July 2026. ", "\nABSTRACT\nThe Russian invasion of Ukraine transitioned from an “existential war” into a “war of attrition.” The study assessed the impact of prolonged conflict on resilience and coping mechanisms through two cross‐sectional assessments conducted with independent samples (Sample 1 – July 2022 [N = 1001]; Sample 2 – November 2023 [N = 2247]). The respondents completed a quantitative questionnaire during the war, which included individual, community, and societal resilience, hope, sense of danger, perceived threats, and posttraumatic stress disorder (PTSD). A significant decrease in all variables was found between Sample 1 and Sample 2 measurements. Path analysis indicated that government support is the variable most strongly related to societal resilience. Community resilience is the variable most strongly related to individual resilience. Perceived threats are the variable most strongly associated with PTSD symptoms. The above‐mentioned variables explain 68% (Sample 1) and 60% (Sample 2) of societal resilience, 19% (Sample 1 and Sample 2) of individual resilience, and 58% (Sample 1) and 12% (Sample 2) of PTSD symptoms. Findings suggest the “routinization” of an ongoing emergency, allowing the population to coexist with the adversity and accept war as the “new normalcy.” Nonetheless, the future remains uncertain, leading to a decline in hope. Strategies that bolster individual and societal resilience during adversities should include social support mechanisms that enhance the population's hope and morale and build the government's trust and support."]

["Journal of Community Psychology, Volume 54, Issue 5, July 2026. ", "\nABSTRACT\nWhile substantial efforts have been made to learn more about youth community violence exposure (CVE) and its wide‐ranging impact, less is known about the effects of different types of CVE on mental health outcomes, particularly internalizing behavior, across contextual factors. The current study examines types of CVE (i.e., hearing/learning about, witnessing, and victimization) across gender, age, socioeconomic status (SES), and racial and ethnic group (White, African American/Black, and Latinx) in a diverse sample of youth seeking treatment at a university‐based pediatric anxiety clinic. Older age (adolescence), male gender, and lower SES were associated with increased rates of CVE. Victimization was positively and significantly correlated with hearing reports of violence against familiars but negatively associated with hearing reports of violence against strangers, suggesting that youth who are victimized often have family or close friends who are also victims of violence, and those who hear about violence against strangers may be safe from victimization in some regards. Results from this study suggest that Black youth, in comparison to White youth, may experience more internalizing symptoms as the result of indirect CVE. For those who witnessed violence against people they know, Latinx youth reported lower levels of anxiety compared to both Black and White youth. In light of these results, potential risk and protective factors associated with CVE and presenting symptoms are discussed.\n"]

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Ahead of Print.

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Ahead of Print.

American Journal of Physiology-Cell Physiology, Ahead of Print.

American Journal of Physiology-Cell Physiology, Ahead of Print.

["Sociology of Health &Illness, Volume 48, Issue 6, July 2026. ", "\nABSTRACT\nThe cultural politics of the ‘problematic’ ageing body have led to a search for solutions in the form of algorithmic technologies. In this article, we look at one problem associated with the ageing body—unintentional falls—and one proposed algorithmic intervention: wearable fall‐detection technology. In dialogue with sociologists concerned with the cultural politics of the older body, we aim to understand what contribution this fledgling technology makes to how the older body is ‘constituted’. To do this, we examine a sample of datasets containing measurements of individuals' movements and falls (which researchers have made available to train algorithms for use in fall‐detection wearables). In contrast to existing attempts to grasp how older users are scripted into technology, which focus on explicit ideas about them, we trace how individual subjects are formatted in these datasets. We find that these individuals become fragmented in the data, rendered into movements abstracted from the bodies that carry them out and the locations in which they take place. The older body is constituted, then, as a risky, deviant set of movements through space, irreducible to its component parts.\n"]

{"p"=>"Diabetic nephropathy (DN) is characterized by a decline in renal function resulting from hyperglycaemia and is often requiring dialysis or renal transplantation. Yet, the signalling events causing DN and the effective treatment options are poorly understood. Changes in the signalling of cyclic nucleotides and their regulated kinases are hypothesized to be involved in its development. Protein kinase A (PKA) signalling pathways are known to modulate extracellular matrix metabolism and exert antifibrotic effects. Multiple isoforms of PKA regulatory and catalytic subunits exist, leading to functional specificities of the kinase arising from different combinations of these isoforms. However, localization of the specific PKA subunits, as well as other signalling proteins involved in this pathway, still need to be explored comprehensively. To gain an overview about PKA distribution, kidneys were analysed by immunohistochemistry and stained for different PKA subunits. Type 1 diabetes was induced by streptozotocin in wildtype (WT) and endothelial NOS knockout (eNOS-KO) mice. The catalytic subunit expression was quantified and compared between healthy and diabetic kidneys. Analysis of expression patterns of the PKA catalytic subunits Cα and Cβ reveal differences across segments of the kidney and in intracellular localization. Cα exhibited ubiquitous expression in all renal cell types. In contrast, Cβ only shows a high expression in proximal tubules, while its expression in other segments is comparatively weak. No significant changes in Cα or Cβ expression are detectable in diabetic mice or eNOS-KO mice compared to WT mice."}

American Journal of Physiology-Renal Physiology, Volume 331, Issue 1, Page F82-F92, July 2026.

["JCMS: Journal of Common Market Studies, EarlyView. ", "\nAbstract\nThis article adopts a political ethnographic approach to follow narrative practices enacted by diplomats and bureaucrats during the trilogue negotiations of the European Union's (EU) Artificial Intelligence Act where inter‐institutional dynamics were at stake. I argue that when diplomats and bureaucrats negotiate AI, they also negotiate their desired position in a struggle over status in EU's diplomatic structures while constructing competing identities of the EU. The narrative analysis shows that three narrative positions endure, ethical and moral; national and economic; supranational and global, which interact through negotiation practices of brokerage and improvisation (re)negotiating social positions and (re)constructing three faces of a European AI identity. These narratives are not performed by a specific diplomat or bureaucrat but remain transversal, competing within and across national, ideological and institutional boundaries. The competing meanings are comprised into the AI Act constituting AI, its governance structure and the EU with ambiguous meanings."]

["Business Ethics, the Environment &Responsibility, EarlyView. ", "\nABSTRACT\nAs environmental concerns reshape corporate landscapes, understanding how Corporate Environmental Sustainability Information Disclosure (CESID) influences financial stability is crucial. This study explores the relationship between CESID and financial default risk in Chinese A‐share listed firms from 2009 to 2020, emphasizing the role of internal control quality and institutional investors as key moderating factors. Using Ordinary Least Squares (OLS) regression with firm‐ and year‐fixed effects, alongside robust econometric techniques including lagged variables, propensity score matching (PSM), entropy balancing, and alternative financial distress measures, we ensure the robustness of our findings. Our results show that higher CESID levels significantly reduce financial default risk, particularly in firms with strong internal controls and greater institutional investor presence. These findings align with agency theory, highlighting governance mechanisms that mitigate information asymmetry, and stakeholder theory, demonstrating how transparency fosters trust and reduces financial distress. This study contributes to the sustainability and finance literature by positioning CESID as a strategic tool for financial risk management in emerging markets. The findings provide important guidance for policymakers and business executives, highlighting the importance of robust governance structures, supportive regulatory measures, and greater transparency in strengthening financial stability and promoting long‐term sustainability.\n"]

["The World Economy, EarlyView. ", "\nABSTRACT\nThis study analyses weekly port calls from 2019 to 2026 to evaluate the Russia–Ukraine war's impact on maritime trade. The data reveals clear structural shifts that Ukrainian traffic moved from high‐risk areas like Odesa to safer Danube River ports. On the other hand, Russia sustained its maritime activity by navigating sanctions and redirecting exports to Asian markets. The Black Sea Grain Initiative also improved navigation conditions for both countries. Overall, the war caused domestic port substitution within Ukraine and a broader logistical reorganization for Russia.\n"]

["Pacific Focus, EarlyView. ", "\nABSTRACT\nThis article examines the adequacy and state practice of employing trade‐related measures to mitigate the global plastic pollution. Trade spans the entire lifecycle of plastics, bringing plastic with high economic value and deep integration within global value chains. As a global environmental crisis, plastic pollution necessitates a synergistic approach to international governance. Discipline in plastic trade under the international legal framework not only helps reconcile the friction between trade and the environment, but also addresses the systemic inefficiencies stemming from regulatory fragmentation. With a focus on three key processes: the Plastic Waste Amendments to the Basel Convention, the WTO Dialogue on Plastic Pollution and Environmentally Sustainable Plastics Trade, and the negotiations toward an international legally binding instrument on plastic pollution, this paper examines the basic paradigms of plastic trade governance and analyzes the deficiencies and geo‐economic obstacles it faces. Given the consideration of global plastic governance's high reliance on state participation, the paper further takes China as a primary case study, analyzing approaches for China to participate in plastic trade governance with the model of foreign‐related rule of law.\n"]

["Medical Anthropology Quarterly, EarlyView. ", "\nAbstract\nThis paper analyzes two disparate experiences of buprenorphine, a medication for opioid addiction, in California. Within the context of the U.S. War on Drugs and after decades of criminalization, buprenorphine represents a shift toward outpatient medical treatment of opioid addiction, but it has been unequally distributed and experienced across geographic settings and populations. Drawing on my interlocutor's description of buprenorphine's “hold,” I interrogate how buprenorphine's symbolic and pharmacological power to embrace, restrain, and otherwise “hold” people arises through its social context. “Holding” is a patient‐driven epistemology, working metaphorically and neurochemically, illustrating raced, classed, and gendered positionalities that simultaneously express and constrain forms of agency and resistance in ideological struggles over the meanings of care in addiction treatment. Buprenorphine's “hold,” or lack thereof, can be read as a neurochemical embodiment of state violence, revealing intensities of carceral forms of “care” and possibilities for transforming addiction treatment meanings.\n"]

["Psychophysiology, Volume 63, Issue 6, June 2026. ", "\nABSTRACT\nHumans comprehend language rapidly, with active prediction of upcoming words as a key mechanism. Studies using sentences have documented facilitations in behavior and brain activity (N400) when people encounter predictable words, and brain responses (anterior positivity) specific to prediction violations. However, it has been challenging to investigate prediction formation mechanisms, given the complex, incremental context provided by sentences. Here, we examined prediction by measuring EEG in a simple word stem completion task. Participants saw three initial letters (e.g., bro___) varying in constraint/entropy of possible completions and were asked to generate a word completion. They then saw a target that was either a probable completion (brother), an improbable completion (bronze), or a pseudoword (*brom). In Experiment 1, participants self‐reported whether the target matched their prediction; in Experiment 2 they made a lexical decision to the target and then typed in their prediction. Consistent with findings from sentences, N400s were reduced for probable completions, primarily driven by a greater proportion of match responses with highly facilitated N400 amplitudes. No anterior positivity was found to improbable words in Experiment 1, but it was present in Experiment 2. Given these task differences, the anterior positivity may therefore reflect engagement of processes to manage activation of lexico‐semantic information when there is competition, as from a strong prediction. Crucially, neural responses following the word stem (i.e., during prediction formation) showed a sustained centro‐posterior positivity that was graded with entropy (more negative for high‐entropy stems). This effect reveals that prediction‐formation processes are sensitive to the distribution of possible completions based on the context.\n"]

["Psychophysiology, Volume 63, Issue 6, June 2026. ", "\nABSTRACT\nNeural oscillations are recognized as a fundamental component of brain electromagnetic activity. They are implicated in a wide range of cognitive processes and proposed as a core mechanism for brain communication. Nonetheless, detecting genuine neural oscillations remains a methodological challenge, particularly due to the difficulty of distinguishing them from aperiodic background activity. To identify episodes of oscillatory activity directly at their sources, we developed sBOSC, which extends the BOSC (Better OSCillation detection) family of algorithms. Consistent with existing approaches, sBOSC detects oscillatory episodes that exceed both a defined power threshold and a minimum duration criterion. In sBOSC, however, the detection of oscillatory episodes also relies on identifying peaks (i.e., local maxima) in the power spectra as well as throughout the brain volume (spatial peaks). Using a series of simulated signals, we tested the ability of sBOSC to detect and localize oscillations across multiple scenarios. Our results show that most oscillatory episodes were accurately detected at their sources, achieving above 95% accuracy under optimal conditions (i.e., high signal‐to‐noise ratio, lower frequencies, and numerous successive cycles). In addition, we validated sBOSC's performance using real magnetoencephalography (MEG) data from both resting‐state and motor task recordings. From the detected oscillatory episodes, we extracted a topographic distribution of natural frequencies that is consistent with previous work, as well as the expected alpha‐ and beta‐band modulations over sensorimotor regions during motor preparation. In conclusion, sBOSC offers a novel approach for identifying oscillatory activity in electrophysiological signals. It extends previous algorithms by operating in source space and verifying the presence of genuine spectral peaks, thereby enabling new possibilities for exploring brain dynamics.\n"]

["Psychophysiology, Volume 63, Issue 6, June 2026. ", "\nABSTRACT\nCommonly used methods for assessing cardiac interoceptive accuracy have been criticized for assuming that all individuals perceive their heartbeat at the same delay following contraction of the heart, despite evidence for notable variability across individuals. However, it remains unclear whether some individuals perceive their heartbeat at a particular phase of their cardiac cycle—that is, at a relative point in the cycle that may vary in absolute timing depending on heart rate—rather than at a specific delay. Identification of all heartbeat perceivers is critical for accurate measurement of cardiac interoceptive accuracy; individual differences in which are theorized to play a role in several aspects of higher‐order cognition as well as health and wellbeing. In the current study, data from 526 participants who completed the Phase Adjustment Task (PAT) as a measure of cardiac interoceptive accuracy were examined. In this task, participants are asked to adjust a virtual dial until tones appear synchronous with their heartbeats. Data were analyzed using a novel framework that allows differentiation between delay‐based and phase‐based response patterns. Of 76 interoceptive individuals identified, 21% (N = 16) demonstrated response patterns consistent only with phase‐based responding. These novel findings challenge current assumptions regarding individual differences in the perception of heartbeats, and suggest that many commonly used measures may underestimate the true proportion of heartbeat perceivers.\n"]

["The Journal of Physiology, EarlyView. ", "\nAbstract figure legend The olfactory bulb input–output transformation was imaged using dual‐colour two‐photon imaging. (Top) Cartoon and histological examples of labelling the olfactory bulb input and output using spectrally distinct optical sensors. (Middle) Modelling and experimental work reveal that input neurons that respond with primarily monotonic concentration‐response relationships are transformed into a mix of monotonic and non‐monotonic responses. (Bottom) Olfactory bulb output state space for a population of three glomeruli with exclusively monotonic responses (black) and with both monotonic and non‐monotonic responses (red). Each trajectory represents a cloud of points that reflects variations in the fluctuations of molecular components present in natural odour stimuli. Monotonic responses alone cluster together, whereas multiple response types broaden coverage of mitral and tufted cell (MTC) state space. Greater coverage of state space makes it easier to discriminate one odour from another, even though the dimension of olfactory bulb state space is greater than 3.\n\n\n\n\n\n\n\n\n\nAbstract\nAnimals can recognize an odour as the same odour across a range of concentrations and discriminate between odours in complex environments. Processing within the mouse olfactory bulb (OB) may be involved, yet the underlying mechanisms remain unclear. Each olfactory receptor neuron (ORN) type maps to the OB in olfactory receptor‐specific channels called glomeruli, where they connect with the dendrites of mitral and tufted cells (MTCs), which project their axons to the rest of the brain. Modelling this transformation yielded predictions about how two kinds of inhibition, local intraglomerular and lateral interglomerular processing, shape MTC output as a function of concentration changes. We confirmed these predictions using in vivo single and dual‐colour two‐photon Ca2+ imaging from the ORNs and MTCs innervating the same glomeruli in the awake mouse OB in response to odours presented across a wide concentration range. We identified a transformation where concentration increases transformed ORN inputs with exclusively monotonically increasing responses into MTC outputs that non‐monotonically increased then decreased, or vice versa. This transformation was odour‐specific, consistent with rising levels of inhibition that scale with excitatory input and predicted by certain ORN characteristics. Therefore non‐monotonic concentration‐response relationships in MTCs are common and expected given how each glomerulus is shaped by feed‐forward excitation, local and lateral inhibition. We propose that this transformation facilitates odour discrimination and the ability to achieve concentration‐invariant odour perception by broadening MTC odour state space.\n\n\n\n\n\n\n\n\n\nKey points\n\nThe role of the olfactory bulb in transforming sensory information remains poorly understood. In the bulb different olfactory receptor neuron (ORN) types map to olfactory receptor‐specific channels called glomeruli, where they interact with the dendrites of mitral and tufted cells (MTCs), which project to the olfactory cortex.\nWe developed a mathematical model detailing how different ORN inputs are transformed by intraglomerular and lateral interglomerular inhibition as a function of odour concentration.\nSingle‐ and dual‐colour in vivo two‐photon Ca2+ imaging of glomerular inputs and outputs across a wide concentration range confirmed some of the predictions.\nIncreasing odour concentration transformed ORN inputs with monotonically increasing responses into non‐monotonic MTC outputs, which responded with increases then decreases, or vice versa. This transformation is heterogeneous, odour‐specific and predicted by certain ORN characteristics.\nThis network transformation broadens the MTC odour state space, providing a mechanistic basis for achieving concentration‐invariant odour perception and fine odour discrimination.\n\n\n"]

["The Journal of Physiology, EarlyView. ", "\nAbstract figure legend Two models of human energy expenditure were tested. The additive model predicts independent resting and activity costs, while the constrained model predicts a tradeoff between resting and active expenditure. Both longitudinal and cross‐sectional experiments support the additive model, with no tradeoffs between resting and active energy expenditures.\n\n\n\n\n\n\n\n\n\nAbstract\nTotal energy expenditure (TEE) is commonly modelled as the sum of resting energy expenditure (REE), activity energy expenditure (AEE), and diet‐induced thermogenesis (DIT). This additive model has recently been challenged by the constrained energy balance model, which proposes that reductions in mass‐adjusted REE compensate to some extent for increases in AEE, rendering mass‐adjusted TEE effectively invariant. We tested these competing models using two complementary approaches. First, we conducted a short‐term longitudinal, repeated‐measures experiment in 12 adults who completed 10‐day periods of high and low physical activity separated by a washout period. TEE was measured with doubly labelled water, AEE with wearable sensors, and REE with indirect calorimetry as well as anthropometric equations. Second, we analysed a cross‐sectional sample of 268 adults from the Pennington Centre Longitudinal Study that measured TEE and REE independently. In both studies, metabolic rates were analysed using size‐adjusted regression models. In the longitudinal experiment, a ∼28% increase in AEE (∼250 kcal/day) increased TEE by 10% (272 kcal/day) without reducing mass‐adjusted REE, contradicting predictions of metabolic compensation. In the cross‐sectional study, mass‐adjusted REE and AEE were statistically independent, with no evidence for metabolic compensation. These results support the additive model of energy expenditure and indicate that increased physical activity does not suppress REE, contradicting the hypothesis that metabolic compensation thwarts the effects of physical activity on weight management.\n\n\n\n\n\n\n\n\n\nKey points\n\nThere is a debate over whether active activity expenditure (AEE) is independent of resting energy expenditure (REE) corrected for body mass and composition or causes decreases in REE through metabolic compensation.\nWe tested AEE's effects on REE using both a repeated measures longitudinal study and a cross‐sectional study. In both studies, AEE and REE were measured independently, and metabolic rates were analysed using regression models.\nIn the longitudinal study, a 28% increase in AEE had no effect on mass‐adjusted REE, contradicting predictions of metabolic compensation. In the cross‐sectional study, mass‐adjusted REE and AEE were statistically independent with no evidence for metabolic compensation.\nThese results indicate that increased physical activity does not suppress mass‐adjusted REE, supporting the additive model of energy expenditure.\n\n\n"]

American Journal of Physiology-Renal Physiology, Ahead of Print.

American Journal of Physiology-Cell Physiology, Ahead of Print.

["Acta Physiologica, Volume 242, Issue 8, August 2026. ", "\nABSTRACT\n\nAim\nThe mammalian tracheal epithelium is composed of different cell types distributed along the proximal‐distal axis. Nevertheless, variations in expression and function of ion channels and transporters participating in fluid absorption and secretion have never been studied separately in proximal and distal mouse trachea. This work aims to characterize basal and stimulated absorption and secretion of fluid obtained from proximal and distal trachea from the same animal.\n\n\nMethods\nUssing chamber was performed using a custom‐made tissue slider allowing small tracheal sections mounting, where response to agonists and blockers was recorded. The role of NKCC1 co‐transporter was studied using the Slc12a2−/− mouse. A genetically tomato‐induced mouse model was used to assess co‐expression of NKCC1 and ASCL3 by immunofluorescence. Animals were instilled with interleukins (ILs) to determine changes in absorption, secretion, and mucus properties.\n\n\nResults\nProximal trachea didn't participate in sodium absorption but exhibited higher cAMP‐ and succinate‐induced anion secretion than the distal section. NBCe1‐dependent bicarbonate and TMEM16A‐driven chloride secretion were significantly higher in distal trachea. NKCC1+ cells were found in the submucosal glands (SMGs) and abundant patches of NKCC1+ cells in the distal region. Isolated NKCC1+ cells co‐expressing ASCL3 were also detected. ILs treatment changed the electrophysiological properties of the distal trachea exclusively.\n\n\nConclusions\nOur experiments determined that the mouse trachea organizes its functions differentially in proximal and distal regions, based on the functional distribution of channels, transporters, and receptors. While the distal trachea changed its responses to agonists inducing anion secretion, the proximal trachea was unperturbed by ILs addition.\n\n"]

{"__content__"=>"\n Graphical Abstract\n \n ", "p"=>[{"__content__"=>"Cellular adaptation to hypoxia is essential for maintaining function and survival. While most hypoxic responss are mediated by hypoxia‑inducible factor signaling, the oxygen‑dependent ADO–RGS (2‑Aminoethanethiol-Dioxygenase—Regulator of G‑Protein Signaling) pathway has recently been implicated in oxygen‑sensitive regulation of G‑protein signaling. The kidneys are particularly vulnerable to hypoxia, a major contributor to chronic kidney disease. Because a systematic characterization of ADO and its RGS substrates across renal cell types is lacking, this study examined their spatial expression patterns in mouse and human kidneys under (patho)physiological conditions. and , , and expression was mapped in mouse kidney sections under normoxic, hypoxic, and fibrotic conditions using RNAscope™, complemented by RT‑qPCR. Mouse data were compared with - expression patterns in human biopsies. expression was uniform across renal regions, cell types, and conditions. Besides its baseline presence in vascular cells, showed strong induction in cortical and outer medullary fibroblasts during anemia. It was also upregulated in fibroblasts and proximal tubules within fibrotic lesions. was highly expressed in vascular structures and demonstrated hypoxia‑induced upregulation in medullary fibroblasts and , with moderate induction under fibrotic conditions. Tubular epithelial expression also occurred during fibrosis. was mostly expressed in interstitial cells in fibrotic kidneys. Human kidney-disease biopsies also displayed distinct and expression patterns. Overall, these findings suggest that while ADO is consistently present, the functional impact of ADO–RGS signaling may be driven by dynamic, cell‑type‑specific regulation of RGS genes during acute and chronic hypoxic stress.", "i"=>[{"__content__"=>"Ado"}, {"__content__"=>"Rgs4"}, {"__content__"=>"Rgs5"}, {"__content__"=>"Rgs16"}, {"__content__"=>"ADO"}, {"__content__"=>"RGS"}, {"__content__"=>"Ado"}, {"__content__"=>"Rgs4"}, {"__content__"=>"Rgs5"}, {"__content__"=>"vasa recta"}, {"__content__"=>"Rgs16"}, {"__content__"=>"Pdgfrb⁺"}, {"__content__"=>"RGS4"}, {"__content__"=>"RGS5"}]}, {}]}

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Volume 331, Issue 1, Page R75-R85, July 2026.

American Journal of Physiology-Lung Cellular and Molecular Physiology, Volume 331, Issue 1, Page L79-L88, July 2026.

American Journal of Physiology-Lung Cellular and Molecular Physiology, Volume 331, Issue 1, Page L70-L78, July 2026.

American Journal of Physiology-Renal Physiology, Volume 331, Issue 1, Page F68-F81, July 2026.

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Volume 331, Issue 1, Page R65-R74, July 2026.

American Journal of Physiology-Lung Cellular and Molecular Physiology, Volume 331, Issue 1, Page L57-L69, July 2026.

American Journal of Physiology-Endocrinology and Metabolism, Volume 331, Issue 1, Page E76-E86, July 2026.

["Health Expectations, Volume 29, Issue 4, August 2026. ", "\nABSTRACT\n\nIntroduction\nReimbursement decisions for orphan drugs are complex, as conventional cost‐effectiveness frameworks may not fully capture broader societal values. To investigate public preferences regarding the inclusion of rare disease drugs in China's Basic Medical Insurance (BMI) using a multi‐center discrete choice experiment.\n\n\nMethods\nFrom July to September 2024, a face‐to‐face, filed‐based discrete choice experiment (DCE) was conducted across four regions in China. Using non probability sampling technique which is known as Quota sampling, participants evaluated drug profiles varying in six attributes. Mixed logit model and latent class model were used for analysis. Relative importance, willingness to pay (WTP), scenario analysis and preference heterogeneity were estimated.\n\n\nResults\nOf the 761 respondents retained after initial data cleaning, 622 passed the internal consistency check and were included in the final analysis. Most participants were urban residents (62.7%), employed (66.6%), and covered by urban and rural resident basic medical insurance (BMI) (57.7%). The general public preferred including orphan drugs in BMI coverage when treatments provided greater health gains, targeted diseases with moderate untreated life expectancy, and lacked existing reimbursed alternatives. In contrast, poorer untreated quality of life and larger increases in BMI financing reduced utility. Health gains were the most important, followed by increases in BMI financing, untreated quality of life, existing BMI coverage, and untreated life expectancy. Annual WTP was ¥1.225 per capita for quality‐adjusted life years (QALY) gains (0.01–4), with lower WTP observed among respondents facing poorer untreated quality of life. Scenario analysis showed that 78.5% would support reimbursement for drugs providing maximal health gains (0.01–4). Preference heterogeneity was observed across age, sex, education, household income, insurance type, and urban–rural residence. Latent class analysis identified two subgroups. The “life‐saving group” (23%) showed strong preferences for greater disease severity and larger health gains, whereas the “pragmatist group” (77%) demonstrated relatively flatter preferences and negative utility associated with declining untreated life expectancy.\n\n\nConclusion\nWhile health gains drive preferences, the public also values equity, disease severity and affordability. Policymakers must integrate these multidimensional social values to ensure legitimacy and fairness in allocating finite resources for rare diseases.\n\n\nPatient or Public Contribution\nMembers of the public were involved in the development of the DCE. In the attribute development phase, members of the public participated in a pilot study to help ensure the clarity and comprehensibility of attribute descriptions and levels. And their feedback informed revisions to the questionnaire. In the main study, members of the public participated as respondents, providing data on societal preferences for orphan drug reimbursement.\n"]

["Bioethics, Volume 40, Issue 6, Page 597-605, July 2026. ", "\nABSTRACT\n(Bio)ethical analysis of space exploration calls for critical reflection on present‐day material and socio‐political contexts. In response to this requirement, this paper first asks how a critical bioethics of space can move beyond a basic four‐principles approach. Having set this initial framework, we arrive at the observation that in political and bioethical discourse a common tendency exists to explain away space activity as ‘inevitable’. This trope requires (bio)ethical attention since portraying human engagement with outer space as a ‘fixed reality’ aligns with dominant political narratives that legitimize control over territory. After this, we outline three additional (value‐laden) lines of reasoning that further reinforce this ideological work as they sustain unwarranted beliefs about what is considered a speculative future and what is not. We then explore the overarching notion of futurity and its impact on bioethical engagement with space exploration. A closer look at such speculative futurism reveals whose ‘humanity’ is being centered and who is envisioned as a part of this future. This paper fits within an understanding of critical feminist and naturalized bioethics that not only brings the arguments used in a bioethical discussion into harsh light but also the boundaries that make this discussion possible in the first place. We aim at practicing a bioethics that, firstly, questions itself as a product of a socio‐political context and, secondly (and relatedly), one in which the question “What is bioethics?” is turned upon bioethics itself.\n"]

["Bioethics, Volume 40, Issue 6, Page 589-596, July 2026. ", "\nABSTRACT\nIn this paper, I argue that negative genetic selection should play a significant role in space exploration and colonization, at least until therapeutic gene editing and repair technologies are cheap and effective enough to enable modification of embryos that would otherwise be selected against and discarded. I present two key reasons supporting this claim. First, there are many traits prospective parents have strong reasons to select against in the Earth context despite the lack of the significant environmental pressures present in space, and these reasons are likely to persist in the context of space exploration and colonization. Second, both in general and in the high‐stakes context of space exploration and colonization, negative selection is likely to be desirable to implement. With regard to the latter context, this is because negative selection can help increase the chances of astronaut survival, mission success, and thriving space colonies by ensuring that astronauts do not have certain traits that would negatively impact those chances. For all these reasons, space bioethicists should avoid prematurely ruling out negative selection as a useful and desirable tool for ensuring that future space exploration and colonization missions have maximally effective and healthy crews.\n"]

["Bioethics, EarlyView. ", "\nABSTRACT\nThe concept of harm is central to medical ethics. In particular, it is frequently used in ethical deliberation about clinical cases and harm‐benefit analyses. Despite its significance, there has been surprisingly little discussion in practice about conceptual approaches and the nature of harm in medical ethics analyses. We examine how different conceptual accounts of harm shape ethical decision making through examples from clinical ethics consultation and data‐intensive medical innovations. By applying three prevailing theoretical‐philosophical frameworks—the counterfactual, temporal, and non‐comparative accounts of harm—to these cases, we demonstrate that explicitly identifying and discussing stakeholders' varying concepts of harm is crucial for ethical analyses in medicine and healthcare. While harm is only one of many considerations influencing medical ethics decision‐making, our analysis reveals that different conceptualisations of harm can lead to substantively different practical outcomes. In this way, how we understand harm can affect recommendation processes, stakeholder communication, and assessments of quality of life and best interests. Without making different types of harm explicit, stakeholders might talk past each other when weighing harm against benefit, as what constitutes harm in one case may not be considered harm in another. We argue that explicit consideration of the nature of harm ensures comprehensive ethical deliberation, and integrates multiple perspectives in healthcare settings. Our findings suggest that the ethical importance of conceptual analysis of harm extends beyond mere theoretical interest, with direct implications for clinical practice and ethical decision making in healthcare."]

["Journal of School Health, Volume 96, Issue 7, July 2026. ", "\nABSTRACT\n\nBackground\nTransgender and gender‐diverse adolescents (TGDA) experience multiple victimization types (i.e., multi‐victimization) more often than their cisgender peers. While greater socioecological supports are associated with reduced victimization, their role in protecting TGDA against multi‐victimization is underexplored.\n\nMethods\nWe conducted a cross‐sectional analysis of health risk behavior survey data from students (N = 4207) across 13 high schools in a mid‐sized U.S. city. We compared victimization rates and socioecological support levels (i.e., parental monitoring, perceived social support, food and housing security) and associations between socioecological support and victimization, accounting for between‐school differences. We included two‐way interactions between gender and socioecological supports.\n\nResults\nTGDA reported more frequent multi‐victimization and lower socioecological support than cisgender adolescents. Across all groups, greater socioecological support was associated with experiencing fewer victimization types. Food security was more protective for cisgender girls than cisgender boys.\n\nImplications for School Health Policy, Practice, and Equity\nEnhancing socioecological support may reduce multi‐victimization for all youth, with TGDA having the greatest need. Schools' advocacy and innovative efforts to bolster socioecological support are critical to TGDA wellbeing.\n\nConclusions\nModifiable socioecological supports may reduce adolescent multi‐victimization. TGDA have lower support rates and higher multi‐victimization rates, suggesting the need for tailored interventions.\n"]

["The World Economy, EarlyView. ", "\nABSTRACT\nThe study focuses on the analysis of neutral states' exports to the Russian Federation via SDID and their comparison with more diligent enforcers of European sanctions, emphasising thus the changes that took place after the Russian invasion of Ukraine in February 2022. The investigation seeks to identify if the invasion and its subsequent repercussions resulted in significant changes in the commodity structure of trade of the neutral states, indicating their engagement in sanction‐busting behaviour. The research is based on 13 synthetic difference‐in‐difference panel data models for each sampled state using data from the UN Comtrade database. The results highlight an increase in the value of sanctioned commodities exported to Russia in all nine instances, where a significant change occurred solely in Kazakhstan and Türkiye. The findings of the study are consistent with the existing literature, and they reveal several directions for future research.\n"]

["Medical Anthropology Quarterly, EarlyView. ", "\nAbstract\nDocumented migrant workers from Indonesia recruited for work in Malaysia need to undergo tuberculosis screenings before being issued work permits and visas. Centered on the production, circulation, and interpretation of chest X‐ray images, these screenings are shaped in concrete, practical ways by the demands of border control regulations requiring them. By focusing on how these screenings are practiced in Indonesian clinics, I argue that migrant tuberculosis screenings in the Indonesia–Malaysia migration corridor enact a distinct form of tuberculosis, co‐determined by its relation to border control—what I call border tuberculosis. The notion of border tuberculosis draws attention to how biomedical practices and standards are adjusted in ways that lend themselves to the selective and productive function of the border. Thus, the article shows that these biomedical screenings are not disinterested instances of data gathering, but constitutive and productive elements of the particular mode of governing borders they are embedded in.\n"]