Anhedonia nonresponse to short-term ketamine administration for treatment-resistant bipolar depression
Therapeutic Advances in Psychopharmacology
Published online on January 31, 2026
Abstract
Therapeutic Advances in Psychopharmacology, Volume 16, XX 2026.
Background:Anhedonia is a key symptom of bipolar depression and a target of ketamine’s rapid antidepressant effects. However, many patients with treatment-resistant bipolar depression (TRBD) do not respond.Objectives:This study aimed to identify clinical ...
Background:Anhedonia is a key symptom of bipolar depression and a target of ketamine’s rapid antidepressant effects. However, many patients with treatment-resistant bipolar depression (TRBD) do not respond.Objectives:This study aimed to identify clinical ...