Although pleasant events figure prominently in behavioral models of depression, little is known regarding characteristics that may predispose people to engage in pleasant events and derive pleasure from these events. The present study was conducted to evaluate genetic and environmental influences on the experience of pleasant events, depressive symptoms, and their covariation in a sample of 148 twin pairs. A multivariate twin modeling approach was used to examine the genetic and environmental covariance of pleasant events and depressive symptoms. Results indicated that the experience of pleasant events was moderately heritable and that the same genetic factors influence both the experience of pleasant events and depressive symptoms. These findings suggest that genetic factors may give rise to dispositional tendencies to experience both pleasant events and depression.